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XB-PHENO-26927

Xtr Wt + neurod2 CRISPR, Sega AG et al. (2019)

Experiment + Assay: Xtr Wt + neurod2 CRISPR + NF42-47 (behavioural assay)
Background: Xtr.Nigerian AKhok
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
CRISPR neurod2 gRNA1 neurod2
 NF stage 2 (2-cell) blastomere
Conditions:
Assay Type Assay Stages Antibody
Other Detection Assay NF stage 42 to NF stage 47  
Anatomical Phenotypes: abnormal swimming behavior, paralysed tail, tail abnormally curved dorsally
Human Disease Associations: early infantile epileptic encephalopathy, epilepsy
Source: Fig 3 AB
Article: XB-ART-55392, PubMed