Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
XB-PHENO-27253

Xtr Wt + TG003, McCluskey KE et al. (2025)

Experiment + Assay: Xtr Wt + TG003 + NF40 (in situ hybridization)
Background: Xtr.Nigerian1NXR
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
chemical TG003
NF stage 25 whole organism
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 40  
Anatomical Phenotypes: abnormal cell migration in neural crest, abnormally localised neural progenitor cell
Expression Phenotypes (1):
mislocalised phox2b expression in migratory neural crest cell
Human Disease Associations: autism spectrum disorder
Source: Fig3a r2c2, 3b
Article: XB-ART-61275, PubMed