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XB-PHENO-27364

Xla wt + CAPE [4uM] (NF8-16), Yoon GH et al. (2025)

Experiment + Assay: Xla wt + CAPE [4uM] (NF8-16) + NF19 (in situ hybridization)
Background: Xla.outbredKXRCR
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
chemical
NF stage 8 whole organism
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 19  
Anatomical Phenotypes: increased width of neural plate
Expression Phenotypes (8):
absent egr2.L expression in cranial neural crest
decreased amount egr2.L expression in hindbrain
decreased amount egr2.L expression in rhombomere R3
absent egr2.L expression in rhombomere R5
decreased amount en2.L expression in midbrain-hindbrain boundary
increased amount hoxb9.L expression in anterior neural tube
decreased amount otx2.L expression in anterior neural tube
decreased amount otx2.L expression in pre-chordal neural plate
Source: Fig.3 B-I, B-II c3r1, c3r2, c3r3, c3r4
Article: XB-ART-61505, PubMed