XB-IMG-116633
Xenbase Image ID: 116633
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Figure 5. Model for the modulation of Wnt/β-catenin pathway by extracellular domains of Frizzled receptors. We propose that a complex formed between Xfz4S and Wnt-3a/-8/-8b could be recognized by LRP and Wnt signaling could be activated in LRP dependent manner. Complexes between Xfz4S and Wnt-4/-5a/-11 would not be recognized by LRP and Xfz4S and Wnt/β-catenin signaling would not be activated by these Wnts. Image published in: Swain RK et al. (2005) Copyright © 2005 Swain et al; licensee BioMed Central Ltd. Creative Commons Attribution license Larger Image Printer Friendly View |