Figure 2. AâH: Spatial expression patterns klf2 (A), klf5 (B), klf6 (C), klf7 (D), klf8 (E), klf11 (F), klf15 (G), and klf17 (H) during Xenopus embryogenesis detected with whole mount in situ hybridization. a, animal view; aa, aortic arches; ad, adenohypophysial placode; an, anterior view, dorsal is up; ba, branchial arches; bl, blastopore lip; cg, cement gland; d, dorsal view, the anterior is up; da, dorsal anterior view; dv, dorsal vegetal view; ey, eye; fb, forebrain; fep, facial epibranchial placode; hb, hindbrain; he, heart anlage; hg, hatching gland; hm, hypaxial muscles; is, intersomitic vessels; l, lateral view, the animal pole is up; la, lateral view, the anterior is up and the ventral is to the left; ld, lateral dorsal view, the animal pole is up; le, lens; li, liver primordium; lu, lung primordium; mb, midbrain; nc, neural crest; np, neural plate; op, olfactory placode; ov, otic vesicle; pcv, posterior cardinal vein; pl, plexus; pn, pronephros; pop, presumptive olfactory placode; ppe, preplacodal ectoderm; prp, preplacodal region; pt, proctodeum; sd, primordia of stomach/duodenum; sm, somite; tg, trigeminal placode; v, ventral view, the anterior is up; vbi, ventral blood island; vg, vegetal view, the dorsal is up. (Xenbase curators note: gene expression is curated in separate images for each panel/ klf gene- see XB article page for isolated images). Image published in: Gao Y et al. (2015) Copyright © 2015. Image reproduced with permission of the Publisher, John Wiley & Sons.Gene Synonyms Species Stage(s) Tissue klf5.L bteb2, cklf, iklf X. laevis Throughout NF stage 10.5 embryo dorsal upper blastopore lip klf6.L bcd1, cba1, copeb, cpbp, gbf, klf6-a, klf6-b, pac1, st12, zf9 X. laevis Throughout NF stage 10.5 dorsal marginal zone marginal zone involuting marginal zone upper blastopore lip klf2.L lklf, Xklf2 X. laevis Throughout NF stage 10.5 ectoderm animal cap mesoderm klf7.L uklf X. laevis Throughout NF stage 10.5 embryo klf8.L LOC108700053 X. laevis Throughout NF stage 10.5 animal hemisphere klf11.L tieg3 X. laevis Throughout NF stage 10.5 upper blastopore lip dorsal embryo klf15.L X. laevis Throughout NF stage 10.5 dorsal embryo klf17.L klf17.1, neptune, zfp393, znf393 X. laevis Throughout NF stage 10.5 animal hemisphere animal cap klf6.L bcd1, cba1, copeb, cpbp, gbf, klf6-a, klf6-b, pac1, st12, zf9 X. laevis Throughout NF stage 11.5 marginal zone dorsal marginal zone involuting marginal zone upper blastopore lip dorsal embryo klf5.L bteb2, cklf, iklf X. laevis Throughout NF stage 15 preplacodal ectoderm anterior placodal area klf8.L LOC108700053 X. laevis Throughout NF stage 15 neural plate neuroectoderm klf11.L tieg3 X. laevis Throughout NF stage 16 neural plate anterior neural fold neuroectoderm non-neural ectoderm klf17.L klf17.1, neptune, zfp393, znf393 X. laevis Throughout NF stage 16 pre-chordal neural plate border cement gland primordium hatching gland klf6.L bcd1, cba1, copeb, cpbp, gbf, klf6-a, klf6-b, pac1, st12, zf9 X. laevis Throughout NF stage 17 preplacodal ectoderm anterior placodal area neural groove neural plate klf2.L lklf, Xklf2 X. laevis Throughout NF stage 17 embryo anterior dorsal klf7.L uklf X. laevis Throughout NF stage 18 dorsal embryo klf15.L X. laevis Throughout NF stage 18 cement gland primordium klf7.L uklf X. laevis Throughout NF stage 25 trigeminal placode klf8.L LOC108700053 X. laevis Throughout NF stage 25 preplacodal ectoderm anterior placodal area klf11.L tieg3 X. laevis Throughout NF stage 25 neural crest otic vesicle optic vesicle klf17.L klf17.1, neptune, zfp393, znf393 X. laevis Throughout NF stage 25 hatching gland cement gland primordium klf2.L lklf, Xklf2 X. laevis Throughout NF stage 26 embryo anterior klf15.L X. laevis Throughout NF stage 26 embryo klf5.L bteb2, cklf, iklf X. laevis Sometime during NF stage 28 to NF stage 41 epibranchial placode facial epibranchial placode foregut stomach duodenum proctodeum trigeminal placode klf6.L bcd1, cba1, copeb, cpbp, gbf, klf6-a, klf6-b, pac1, st12, zf9 X. laevis Sometime during NF stage 29 and 30 to NF stage 40 posterior cardinal vein trigeminal placode cement gland vascular plexus spinal cord brain forebrain midbrain klf7.L uklf X. laevis Throughout NF stage 32 heart trigeminal ganglion adenohypophyseal placode forebrain telencephalon intersomitic region pharyngeal region klf8.L LOC108700053 X. laevis Throughout NF stage 32 ventral blood island tail brain forebrain midbrain hindbrain pharyngeal arch mandibular arch hyoid arch branchial arch somite trunk somite tail somite eye klf11.L tieg3 X. laevis Throughout NF stage 32 otic vesicle eye brain forebrain midbrain hindbrain neural crest pharyngeal arch klf17.L klf17.1, neptune, zfp393, znf393 X. laevis Throughout NF stage 32 cement gland pharyngeal arch mandibular arch hyoid arch branchial arch head ventral blood island hematopoietic stem cell posterior ventral blood island anterior ventral blood island klf5.L bteb2, cklf, iklf X. laevis Throughout NF stage 33 and 34 olfactory placode pharyngeal arch otic vesicle head klf2.L lklf, Xklf2 X. laevis Throughout NF stage 33 and 34 posterior cardinal vein blood vessel vascular endothelium endothelial cell vascular plexus intersomitic region intersomitic vessel head vasculature tail tip tail tail bud klf6.L bcd1, cba1, copeb, cpbp, gbf, klf6-a, klf6-b, pac1, st12, zf9 X. laevis Throughout NF stage 3 (4-cell) embryo animal pole klf2.L lklf, Xklf2 X. laevis Throughout NF stage 3 (4-cell) animal pole klf7.L uklf X. laevis Throughout NF stage 3 (4-cell) animal hemisphere klf8.L LOC108700053 X. laevis Throughout NF stage 3 (4-cell) animal hemisphere klf15.L X. laevis Throughout NF stage 3 (4-cell) embryo animal blastomere klf6.L bcd1, cba1, copeb, cpbp, gbf, klf6-a, klf6-b, pac1, st12, zf9 X. laevis Throughout NF stage 35 and 36 posterior cardinal vein hypaxial muscle cement gland brain forebrain midbrain hindbrain trigeminal ganglion otic vesicle spinal cord pharyngeal arch foregut hepato-pancreatic progenitor cell liver vascular plexus klf15.L X. laevis Throughout NF stage 35 and 36 head eye otic vesicle brain pronephric kidney somite trunk somite tail somite intersomitic region post-anal gut proctodeum klf7.L uklf X. laevis Throughout NF stage 37 and 38 brain forebrain midbrain hindbrain eye lens otic vesicle pharyngeal region klf6.L bcd1, cba1, copeb, cpbp, gbf, klf6-a, klf6-b, pac1, st12, zf9 X. laevis Throughout NF stage 39 liver vascular plexus head brain cranial ganglion pharyngeal arch klf15.L X. laevis Throughout NF stage 39 head brain eye pronephric kidney somite trunk somite tail somite klf6.L bcd1, cba1, copeb, cpbp, gbf, klf6-a, klf6-b, pac1, st12, zf9 X. laevis Throughout NF stage 40 lung primordium head klf11.L tieg3 X. laevis Throughout NF stage 40 otic vesicle head brain pharyngeal arch head mesenchyme klf5.L bteb2, cklf, iklf X. laevis Throughout NF stage 4 (8-cell) embryo animal hemisphere animal blastomere klf11.L tieg3 X. laevis Throughout NF stage 4 (8-cell) animal blastomere klf17.L klf17.1, neptune, zfp393, znf393 X. laevis Throughout NF stage 4 (8-cell) animal hemisphere animal blastomere klf5.L bteb2, cklf, iklf X. laevis Throughout NF stage 9 embryo animal hemisphere klf6.L bcd1, cba1, copeb, cpbp, gbf, klf6-a, klf6-b, pac1, st12, zf9 X. laevis Throughout NF stage 9 animal hemisphere klf2.L lklf, Xklf2 X. laevis Throughout NF stage 9 animal pole klf7.L uklf X. laevis Throughout NF stage 9 animal hemisphere klf8.L LOC108700053 X. laevis Throughout NF stage 9 animal hemisphere klf11.L tieg3 X. laevis Throughout NF stage 9 animal hemisphere klf17.L klf17.1, neptune, zfp393, znf393 X. laevis Throughout NF stage 9 animal hemisphere animal cap
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