Xenbase Image ID: 43341

Figure 1. Zic1 regulates the expression of direct target genes in whole embryos. The expression patterns by in situ hybridization are shown. A-C: aqp-3b. D-F: cpl-1. G-I: CRABP-II. J, K: tnrc4. L, M: Xl.25952. N, O: Xl.8933. P, Q: myoD. A, D, G, J, L, N, and P are uninjected embryos illustrating the expression of aqp-3b, cpl-1, CRABP-2, tnrc4, Xl.25952, Xl.8933, and myoD, respectively. B, E, H, K, M, O, and Q show reductions in gene expression produced by injection of RNA for a dominant interfering construct of zic1 (zic1 Delta N, previously called dnzic1; Li et al.,[2006]; Merzdorf and Sive,[2006]). C, F, and I show increases in gene expression resulting from injection of full-length zic1 RNA. One cell of 2-cell embryos was injected with either 100 pg zic1 RNA or 100 pg zic1 Delta N RNA together with 25 pg lacZ RNA. Stage 15-18 neurula stage embryos are shown. Arrowheads mark the injected sides. Image published in: Cornish EJ et al. (2009) Copyright © 2009. Image reproduced with permission of the Publisher, John Wiley & Sons. Gene Synonyms Species Stage(s) Tissue aqp3.S aqp-3, aqp3-a, aqp3-b, aqp-3b, aqp3b, AQP-x3, Aquaporin-3, aquaporin-3b X. laevis Throughout NF stage 16 neural plate border pre-chordal neural plate border chordal neural plate border preplacodal ectoderm ptgds.S cerebrin-28, cpl-1, cpl1, lipocalin, l-pgds, lpgds, pds, pgd2, pgds, pgds2, ptgds-a, ptgds-b, XlCpl1 X. laevis Throughout NF stage 16 anterior neural ridge pre-chordal neural plate border sp7.L osterix, osx X. laevis Throughout NF stage 16 anterior neural ridge neural plate border pre-chordal neural plate border chordal neural plate border myod1.S mf25, MyoD, myod1-a, myod1-b, myogenic factor 3, XMyoD, XtmyoD X. laevis Throughout NF stage 16 paraxial mesoderm presomitic mesoderm crabp2.L xCRABP X. laevis Throughout NF stage 18 preplacodal ectoderm neural plate chordal neural plate anterior neural ridge celf3.L brunol1, cagh4, celf3-a, celf3-b, erda4, etr-1, etr1, tnrc4 X. laevis Throughout NF stage 18 neural plate preplacodal ectoderm dgat2.L X. laevis Throughout NF stage 18 neural plate border neural crest Image source: Published Larger Image Printer Friendly View

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